Application Note

Quality Analysis of Circulating Cell-Free DNA from Indivumed Service’s Plasma Sample Collection

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Cell-free circulating DNA (cfDNA) fragments are found in various body fluids, including blood plasma, urine, sputum, cerebrospinal fluid, pleural fluid, cyst fluid, and saliva. Molecular analysis of cell-free tumor DNA (ctDNA) from liquid biopsies is gaining importance in various oncology-related clinical applications such as diagnosis, prognosis, therapy selection, and/or monitoring.

Learn how we have implemented blood collection and plasma processing procedures to meet the need for high-quality cfDNA. In this study, the quality and quantity of plasma cfDNA isolated from blood collected from various patients within Indivumed Services’ Clinical Network was evaluated.

Download this Application Note to Learn About:

  • How blood collection and plasma preparation was processed, using several methods for evaluation of concentration, yield, and quality of cfDNA.

  • The outcome of using isolation of cfDNAs from plasma samples and how using a control revealed low probably of gDNA contamination of cDNA from double spun plasma samples.

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